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Phenibut: effects, advantages, euphoria, overdose

Side Effects of PhenibutPhenibut is a supplement which may be used as a smart drug. In this role it is helpful for alleviating symptoms of tiredness, insomnia, stress, nervousness and depression. Phenibut is an anxiolytic with proven abilities to elevate mood and soothe anxiety. 
Some Phenibut user reviews suggest this nootropic may be a more effective anxiolytic than the more traditional and commonly-prescribed drugs. Phenibut may also be used as a cognitive enhancer as it can increase memory and sharpen focus, as well as stimulate general mental abilities.
Below we cover the benefits and effects of Phenibut in greater detail and outline how it should be used for maximum results.
Effects of Phenibut
Phenibut was created by Soviet scientists in the 60s at the Russian Academy of Medical Sciences. It is available via prescription in Russia but in the USA it’s classified as an over-the-counter (OTC) supplement. Therefore, no prescription is required for Phenibut within the US. 
Phenibut is derived from the gamma-Aminobutyric acid (GABA) neurotransmitter. An additional phenyl ring is found in its unique molecular structure. This seemingly insignificant addition brings a profound benefit; whereas GABA alone cannot cross the blood-brain barrier when taken as a supplement, Phenibut is entirely able to cross directly into the brain.
Phenibut’s method of action is to bind with GABA neural receptors and so reduce the amount of stimulatory impulses in the brain. Phenibut interfaces directly with neural GABA receptors and in so doing brings about a reduction in subjective feelings of stress, agitation and anxiety.
GABA is thought to be the primary inhibitory neurotransmitter. Its role is to act against those other neurochemicals which cause neurological excitement and mental stimulation (which sounds positive but can be negative, eg. stress, anxiety or pain sensations). The brain is generally able to regulate itself to avoid over-excitement however in serious stress or anxiety conditions this self-regulation process can break down. In such cases, a GABA mimic like Phenibut reduces the excess neuronal firing and restores equanimity. This will reduce anxiety, obsessions, irritability, hyperactivity and the like.
The so-called Phenibut high results from the supplement’s ability to balance out brain activity, bringing peace to a hyperactive mind. The effect is the same as if a regular level of GABA was present, preventing neurons from activating unnecessarily. This brings a subjective experience of calm and harmony. 
Using Phenibut may lead to greater ease in entering slumber. It may also improve your concentration on the task in hand and free energy from negative ideation for use on more productive tasks. One more effect of Phenibut is that it is somewhat stimulatory to your brain’s reward mechanism; the dopamine receptors. High dopamine levels are associated with feelings of pleasure and even ecstasy. Dopamine neurons are activated to reward you for adaptive behaviors, such as eating or having sex. This also helps to explain the Phenibut high… 
Dopamine also plays a role in other brain functions, such as concentration, awareness and impulse control. By raising dopamine levels, Phenibut may act as a mood enhancer and increase your natural ambition and drive.
Effects of Phenibut
Advantages of Phenibut
Phenibut’s major beneficial effect is the reduction of anxiety without any cognitive impairment; a common side effect of most tranquilizers. The majority of competing anxiolytics don’t bring the same kind of “natural” rebalancing as Phenibut and generally, they reduce mental effectiveness in some way. For example, they may make driving or operating machinery dangerous by reducing your focus, awareness and responsiveness.
Phenibut will have no such negative effects upon your regular mental function. Research in humans has proved that mental abilities are in fact increased by this smart drug. Combined with less anxiety and stress, this leads to improved recall, learning and general brain function. Phenibut is even helpful if you find it difficult to get to sleep; it will likely bring deeper and more refreshing sleep.
Side Effects of Phenibut
The good news is that Phenibut has very few harmful or unpleasant effects. Generally speaking, so long as you take the proper dosage and use it only as recommended, you won’t experience side effects. 
To avoid any ill effects, it’s important to take the right dose, which can range from 500 to 1500 mg. You should also phase your usage so as to stop tolerance developing. This means that you should avoid using Phenibut for days, weeks or even months at a stretch, so that the body does not get too used to it, require ever greater quantities for the same effect and ultimately become dependent on Phenibut. To avoid tolerance developing, you shouldn’t take Phenibut for more than three days consecutively and you should allow a week to elapse between such usage periods.
Used properly in the manner described above, Phenibut is likely to be well-received in your body. However, occasionally minor adverse effects are reported in some users. The most commonly reported side effect is having intense dreams and sometimes nightmares. This occurs due to the enhanced REM (Random Eye Movement) sleep mode which results from Phenibut usage. During the dream phase of sleep, the brain sorts through memories and learning and Phenibut aids in this process. Intense dreams indicate that the drug is effective.
Other side effects which are sometimes encountered include sleepiness, stomach complaints, queasiness, numbness and minor withdrawal symptoms after Phenibut is discontinued. The withdrawal can resemble alcohol’s hangover effect. However, these symptoms are only likely to arise if you take Phenibut in excess. 
The positive effects of Phenibut vastly outweigh its drawbacks, provided it is used as indicated.
Side Effects of Phenibut
Phenibut Overdose - Recreational Use
Excessive quantities of Phenibut greater than 2 g. may result in a form of intoxication reminiscent of the effects of alcohol or benzos. Users experience reduced coordination, forgetfulness and impaired speech. 
Overdosing on Phenibut is potentially harmful and may result in hospitalization. Various hospital emergency rooms (ERs) state that they are seeing more incidents of Phenibut abuse. Given that Phenibut is available without prescription as a supplement (at least in the US), it is perhaps inevitable that it is being abused in this way. Serious side effects are possible and addiction, dependence and withdrawal symptoms are all likely outcomes if Phenibut is regularly abused.
Getting euphoria from Phenibut
The fact is that recreational use of Phenibut in means of getting euphoria from Phenibut, has many potentially harmful and unpleasant side effects, such as “Phenibut hangover,” and its recreational use is nowhere near enjoyable enough to risk such side effects. Those taking Phenibut for insomnia, social anxiety and other conditions which are related to hyperactive neurons will likely receive more benefit from the assistance of a mental health professional. Using Phenibut at night as a sleep or simply to get euphoria aid will often lead to hangover sensations and a headache in the morning. Phenibut addiction and withdrawal is a known and studied phenomenon.
The most effective alternative to Phenibut is likely Tianeptine, which is an anxiolytic with no GABA involvement. Tianeptine enhances mood due to its interaction with mu-opioid recpetors, among other sites of neural interaction. Mu-opioid receptors are responsible for the so-called runner’s high, which should give some idea of Tianeptine’s subjective effect

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